Minggu, 27 Juni 2010

Open Source in Medical Imaging and Collaboration.


iPath is providing an free and open platform for "case based collaboration", especially designed for medical applications (telemedicine, etc). The iPath-Server package provides a sort of medical BBS to discuss/consult cases online. Additional modules may be added.

I have been using their free web-based service for the past few years and found it very flexible and usable. It is also quite popular amongst many pathologists i know, who use the iPath server to collaborate on difficult Cytology/Histopathology cases. 

http://sourceforge.net/projects/ipath/

Selasa, 22 Juni 2010

What Really Causes Acne

When you're suffering from acne, you just want to know one thing: "How do I get rid of it and become Acne Free?" However, taking the time to learn exactly what acne is will help you find the right solution. Once you understand the real causes of acne, you'll be in a much better position to sort through all the different remedies and spot "quack medicine" for what it is.

Many people blame hormones and natural body oils for causing acne. In fact, it's much more complicated than that. Acne is caused by a combination of clogged pores, bacteria, hormones, and an aggressive immune system.

You probably know that your skin is covered with tiny openings called hair follicles, or pores. Attached to each pore are glands that produce a natural oil called sebum. The pores are lined with specialized skin cells called keratinocytes. These cells have a limited life span and eventually slough off after they die. Usually they're flushed out by the sebum and get rinsed off the next time you take a shower. However, sometimes these follicular cells react abnormally to the hormones your body produces, mostly male hormones called androgens. Men and women naturally produce androgens from the time they it puberty, which is why children usually aren't plagued with acne until they become teenagers.

The cells in your pores react to these hormones by becoming thick and sticky. The sticky dead cells form a plug that blocks the pore, trapping the sebum oil. Initially this results in noninflammatory acne, otherwise known as whiteheads and blackheads.

Tender red acne forms mostly as a result of a bacterium called P. acnes. This bacterium thrives in dark, warm, oily places where it's exposed to little oxygen--which perfectly describes your pores! But the problem really begins with your immune system, which sees P. acne as a serious threat and launches a full-scale attack. P. acne is pretty harmless, so this response is a bit like using dynamite to kill a mouse. This causes the acne to become even more sensitive, inflamed, and prone to scarring.

Although diet, stress, and other factors may not be a direct cause of acne, many experts now agree that they definitely play a role. For example, recent studies confirmed that stress can increase the production of androgen hormones, which in turn encourages keratocyne cells to clump together and plug your pores.

Unfortunately, there is no cure for acne. However, it can be controlled. By keeping track of your acne triggers and using an appropriate skin regimen, you'll rid yourself of those annoying pimples and enjoy clear skin again becoming Acne Free.

Dan Lund is the Webmaster of The Yellow Ads.com for more information and resources please visit http://www.theyellowads.com our site index is there to help you find the information you are looking for.

Kamis, 17 Juni 2010

Mapping Asthma - GPS in Clinical and Preventive Medicine

Came across this wonderful use of Global Positioning System in medicine. 

The Spiroscout inhaler tracker on Asthmapolis.


By tracking the use of inhalers, Asthmapolis aims to help patients and physicians improve management of asthma and provide a valuable new source of aggregated, anonymous and voluntarily shared data for scientists and public health.

The tracker can simply be attached to the top of the inhaler . It records the times and locations when the inhaler is used and this data can be viewed in real time over handheld devices like phones to create a complete clinical diary of events.This lets you map and track your asthma.

Besides, Physicians who remotely monitor asthma symptoms and the use of medications by their patients can identify those in need of additional attention, and help them achieve better asthma control.  This would also provide very valuable real time data on trends in Asthma attacks amongst various populations and in specific geographical areas.



You can find them on Facebook  and also follow their efforts on Twitter.

Jumat, 11 Juni 2010

Online Collaboration in Proteomic Research



Antigen-Antibody reactions are the basis of many physiochemical experiments. The primary step in producing antibodies is identifying a potential epitope. Epitopes are distinctive markers that protrude from the surface of an antigen, and that alert the immune system to the antigen's presence. Finding suitable epitopes is a tough task and many months may be wasted searching for the elusive target .Researchers at Germany’s Heidelberg University have now set up an open access web portal to aid proteomic research through the exploration of epitopes. This portal lets you conduct a 'virtual experiment' to find out how many antibodies you need and against which targets.



EpiC (The Epitope Choice Resource) aims to provide physio chemical predictions of antigenicity together with functional annotation in order to provide the user with adequate information in order to make a decision about the best location of an epitope for an antibody based experiment. The project connects to a wide range of servers throughout Europe and was funded by the EU Framework 6 networking action ProteomeBinders.
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